2022 was an eventful year with lots of ups and downs. While the global economy is struggling, and problems like climate change and social instability continue to grow, there have also been some significant technological and scientific breakthroughs.

The most prominent developments probably happened in deep learning with the appearance of generative models that are able to generate human-level music, art, dialog, and code. In this context, I want to talk about two specific papers that shaped the field this year and most likely next year. The paper “Denoising Diffusion Probabilistic Models”  which is the basis for Dall-E 2, Stable diffusion, and many other generative models, and the chinchilla paper from Deepmind, which demonstrated the importance of high-quality training data over model size. This will likely shape the design and cost of future models, including the anticipated release of OpenAI’s GPT-4 in 2023, which is expected to outperform humans in many text-based tasks. The improvements are not only driven by Moore’s law and architectural improvements but also the money spent to train and develop these systems increases. This is expected as the potential is more and more recognized and the value these systems provide is ever-increasing.

Note that this is a logarithmic chart. the growth is nearly double exponential.

But not just GPT-4. AI will continue to disrupt various industries such as search and creative writing and spark public debate about its impact, even more than is happening right now. It will also lead to the production of high-quality media with fewer people and resources thanks to AI’s assistance. In the field of 3D generation, I expect to see similar progress in 2023, bringing us closer to the quality of 2D generation.

Fusion, the process of combining atomic nuclei to release a large amount of energy, has made significant strides in recent years. This is largely due to the incorporation of machine learning and advancements in various fields such as materials science and engineering. Recently, the U.S. Department of Energy announced that they were able to achieve a positive net outcome from a fusion reaction, which is a major milestone in the pursuit of unlimited clean energy. While I expect to see continued progress in this field, it is unlikely that we will see a commercial fusion reactor within the next two years. However, the upcoming start of the Iter project, an international collaboration to build a fusion reactor, may refuel interest and drive further developments in this promising area.

The James Webb Space Telescope (JWST) is an important milestone in the field of astronomy because it is designed to be the most powerful and advanced space telescope ever built. It started to operate this year. It is a collaboration between NASA, the European Space Agency (ESA), and the Canadian Space Agency (CSA). One of the main goals of the JWST is to study the early universe and the formation and evolution of galaxies. It will be able to observe some of the most distant objects in the universe, including the first stars and galaxies that formed after the Big Bang. In addition to studying the early universe, the JWST will also be able to observe exoplanets (planets outside of our solar system) and potentially search for signs of life on these planets. It will have the ability to study the atmospheres of exoplanets and look for biomarkers, such as oxygen and methane, which could indicate the presence of life. The JWST is also expected to make important contributions to our understanding of planetary science, by studying the atmospheres and surfaces of planets in our own solar system and beyond.

The James Webb Space Telescope (JWST)

The hardware industry has faced challenges this year due to manufacturing bottlenecks. Despite the continuation of Moore’s law and the development of new alternatives to silicon, it has been difficult to obtain chips at this time. The industry is restructuring in order to better handle future demand for hardware. Specialized hardware, such as AI processors and quantum computers, are seeing rapid development. According to IBM’s roadmap, we can expect to see quantum computers with over 1000 Qbits in the upcoming year. GPUs will become more important with the rise of AI. However, these advancements in hardware technology also come with the need for careful consideration and planning in terms of production and distribution. Ensuring a stable and efficient supply chain will be crucial in meeting the increasing demand for these specialized hardware components.

Virtual Reality (VR) technology has experienced a difficult period in recent years due to overhyping of its potential. While some people may have expected VR to revolutionize the way we interact with and experience the world, it has yet to reach the level of ubiquity and practicality that was promised by Meta. But the year 2023 is shaping up to be a promising one for the VR hardware market, with multiple new headsets, such as the Quest 3, and maybe even an Apple Headset, set to be released. These new products will likely offer improved graphics, more intuitive controls, and a wider range of content and experiences. While it may not fully realize the vision of a “Metaverse”, VR is still likely to be a great entertainment product for many people

2023 will be a critical year for AR. It will be the first time that we can build affordable Hardware in a small form factor. Chips like the Snapdragon AR2 Gen 1 implement Wifi 7 and low energy usage and will make it possible to build Smart glasses. Depending on the availability and price of the chips and other components I expect glasses from many different companies with even more capabilities than Oppo air Glass 2.

One of the most exciting developments in computer interfaces is the emergence of brain-computer interfaces (BCIs). These allow for direct communication between the brain and a computer, enabling the possibility of controlling devices with thought alone. While companies like Neuralink are claiming to begin human trials next year, non-invasive BCIs present a much lower barrier to entry and are being actively developed by startups such as Synchron, which has received significant funding. AI will also help the field by decoding brain signals. It is likely that we will see at least one viral video showcasing the capabilities of these non-invasive BCIs, similar to the viral video of a monkey playing pong using a BCI that was released last year. The potential applications for BCIs are vast and diverse, ranging from medical and therapeutic uses to gaming and everyday tasks. As these technologies continue to evolve, it is exciting to consider the possibilities for the future of human-computer interaction.

Researchers from biotech and other fields were able to develop an mRNA vaccine for COVID-19 in less than a year. The same technology was also used to create a universal flu vaccine and a vaccine for malaria. The combination of biology and AI has yielded promising results in the development of treatments for various viruses and illnesses. For example, a team led by Chris Jones of the Institute of Cancer Research used AI tools to identify a new drug combination to fight diffuse intrinsic pontine glioma, a type of incurable childhood brain cancer. The proposed combination extended survival in mice by 14% and has been tested in a small group of children. Additionally, Dr. Luis A. Diaz Jr. of Memorial Sloan Kettering Cancer Center published a paper in the New England Journal of Medicine describing a treatment that resulted in complete remission in all 18 rectal cancer patients who took the drug. Overall, the progress in the field is accelerating thanks to advancements in AI, such as Alphafold 2, which are designed to find and develop treatments for various diseases. If this continues we will be able to beat cancer in the next few years, which leads to the next field.

I predict that every person under 60 has the potential to live forever, as I mentioned in my post about longevity escape velocity. The field of aging research has made significant progress in recent years and is more confident than ever in its understanding of the aging process and life itself. For example, researchers at the Weizmann Institute of Science in Israel were able to create fully synthetic mouse embryos in a bioreactor using stem cells cultured in a Petri dish, without the use of an egg or sperm. These embryos developed normally, starting to elongate on day three and developing a beating heart by day eight. This marked a major advancement in the study of how stem cells form different organs and how mutations can cause developmental diseases. This is a promising step toward the end goal: Achieving complete control over all biological processes in the body.

While this was a slow year in some aspects, major progress was made in most fields, and 2023 will be even faster. We are at the knee of an exponential blowup and we are not ready for what is coming. While I am still worried about how society will react and adapt, I am excited for 2023 and the rest of the decade.